Genome-wide mapping of protein-DNA interaction dynamics

Abstract: We recently introduced new tools for high-resolution genome-wide chromatin profiling and have applied them to study chromatin organization and dynamics in a variety of model systems, including yeast, flies and mammals. Among the questions addressed are: How do transcription factors find their binding sites in DNA packaged into nucleosomes? How are nucleosomes depleted from gene regulatory regions? What is the relationship between nucleosome deposition pathways and chromatin deregulation in disease? Our findings illustrate ways in which chromatin dynamics can play a central role in regulating gene expression and silencing.

biochemistrycancer biologychemical biologycell biologydevelopmental biologydrug discoveryevolutiongeneticsimmunologymolecular biologymicrobiologyneuroscienceplant sciencessystems biologybiotechnologybiological techniquesbiophysics

Audience: researchers in the discipline

( video )

Comments: Organizers can be contacted at m.tariq@lums.edu.pk or 22100032@lums.edu.pk for the zoom link.

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Colloquium zooming Molecular & Cellular Biology LUMS

Series comments: Zooming Molecular & Cellular Biology Colloquium was initiated on July 28th, 2020 by the Biology department at Syed Babar Ali School of Science & Engineering (SBASSE), Lahore University of Management Sciences (LUMS). The series follows through various topics which come under the ambit of Molecular and Cellular Biology and we’ve had the pleasure and honor of hosting some of the most knowledgeable scientists from around the globe. Organizers can be reached out at 24100162@lums.edu.pk or 24100001@lums.edu.pk for the Zoom link of individual talks. All lectures are LIVE streamed on SBASSE's official Facebook page.

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