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SUMMARY:Prof. Dr. Steve Henikoff (Fred Hutchinson Cancer Research Center)
DTSTART:20210303T040000Z
DTEND:20210303T050000Z
DTSTAMP:20260423T022843Z
UID:MCB_LUMS/15
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/MCB_LUMS/15/
 ">Genome-wide mapping of protein-DNA interaction dynamics</a>\nby Prof. Dr
 . Steve Henikoff (Fred Hutchinson Cancer Research Center) as part of Collo
 quium zooming Molecular & Cellular Biology LUMS\n\n\nAbstract\nWe recently
  introduced new tools for high-resolution genome-wide chromatin profiling 
 and have applied them to study chromatin organization and dynamics in a va
 riety of model systems\, including yeast\, flies and mammals. Among the qu
 estions addressed are: How do transcription factors find their binding sit
 es in DNA packaged into nucleosomes? How are nucleosomes depleted from gen
 e regulatory regions? What is the relationship between nucleosome depositi
 on pathways and chromatin deregulation in disease? Our findings illustrate
  ways in which chromatin dynamics can play a central role in regulating ge
 ne expression and silencing.\n\nOrganizers can be contacted at m.tariq@lum
 s.edu.pk or 22100032@lums.edu.pk for the zoom link.\n
LOCATION:https://researchseminars.org/talk/MCB_LUMS/15/
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