Biological effects of radiation: from initial footprints to therapy and radiation protection applications

Abstract: The Radiation Biophysics and Radiobiology Laboratory of the University of Pavia is hosted in the “A. Volta” Physics Department, Pavia, Italy. Within national and European research projects, we study the effects of ionizing radiation on biological structures. Our work includes experimental and theoretical approaches. Experimental measurements are routinely performed on in vitro and ex-vivo cell cultures and tissues. In parallel, physics-based and mathematical computational models are used to gain mechanistic insight into cell responses to radiation. Besides studies on fundamental radiobiological mechanisms elicited by varied radiation qualities or background environmental radiation, different projects focus on applications to radiation therapy and its optimization, as well as radiation protection, in particular on low-dose exposures and the space radiation environment. In this seminar, we will briefly review a selection of the more recent research accomplishments of the Lab. This includes ongoing projects on the optimization of combined chemo- and immuno-therapy treatments with radiotherapy, studies of space-radiation related health risks and risks of nuclear workers accidentally exposed to peculiar radioactive products as micrometric metal particles.

bioinformaticscancer biologycell biologymolecular biologysystems biology

Audience: researchers in the topic

RadBio Seminars