BEGIN:VCALENDAR
VERSION:2.0
PRODID:researchseminars.org
CALSCALE:GREGORIAN
X-WR-CALNAME:researchseminars.org
BEGIN:VEVENT
SUMMARY:Massimiliano Esposito (University of Luxembourg)
DTSTART:20220324T163000Z
DTEND:20220324T170000Z
DTSTAMP:20260421T125023Z
UID:MoRN/50
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/MoRN/50/">Fr
 ee energy transduction in chemical reaction networks from enzymes to metab
 olism</a>\nby Massimiliano Esposito (University of Luxembourg) as part of 
 Seminar on the Mathematics of Reaction Networks\n\n\nAbstract\nI will rigo
 rously define energy transduction in open chemical reaction networks (CRNs
 ). The method is based on the stoichiometric matrix and the chemostatted s
 pecies to identify the fundamental set of thermodynamic forces and fluxes 
 contributing to the CRN dissipation at steady state. Transduction arises w
 hen some fluxes flow against their force thus creating negative contributi
 ons to the dissipation. This is possible because other fluxes power transd
 uction by being aligned with their force and ensuring the overall positivi
 ty of the dissipation. Transduction is an emergent phenomenon arising at t
 he network level because fluxes of elementary reactions are always aligned
  with their force. I will apply our method to study the efficiency of meta
 bolic pathways in central metabolism. Our method generalizes to arbitrary 
 (nonlinear) CRNs the work by Terrell L. Hill on free energy transduction i
 n pseudo first order (linear) CRNs.\n
LOCATION:https://researchseminars.org/talk/MoRN/50/
END:VEVENT
END:VCALENDAR