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SUMMARY:Christoph Allolio (Mathematical Institute\, Charles University)
DTSTART:20250505T134000Z
DTEND:20250505T151000Z
DTSTAMP:20260405T175450Z
UID:NSCM/179
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/NSCM/179/">A
 pplied Continuum Modeling of (Sub)cellular Morphogenesis</a>\nby Christoph
  Allolio (Mathematical Institute\, Charles University) as part of Nečas S
 eminar on Continuum Mechanics\n\nLecture held in Room K3\,  Faculty of Mat
 hematics and Physics\, Charles University\, Sokolovská 83  Prague 8..\n\n
 Abstract\nCellular phenomena at the microscopic level are usually modeled 
 via molecular simulations. These simulations have the advantage of giving 
 an accurate description of the molecular interactions that give rise to bi
 ological phenomena. However\, they are computationally expensive and hard 
 to interpret. In particular\, they are not capable of giving a satisfactor
 y view of slow processes\, such as organelle morphogenesis or cell divisio
 n. For this purpose\, continuum models are preferable. These models can be
  validated by structural data (e.g. electron microscopy). However\, they c
 an also be directly parametrized by molecular simulations. I present such 
 a "data-driven" model for large membrane deformations\, e.g. induced by ce
 ll penetrating peptides as well as a more reductive morphoelastic model fo
 r bacterial division.\n
LOCATION:https://researchseminars.org/talk/NSCM/179/
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