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SUMMARY:Anna Hundertmark (Rheinland-Pfälzische  Technische Universität)
DTSTART:20241007T134000Z
DTEND:20241007T151000Z
DTSTAMP:20260405T174623Z
UID:NSCM/152
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/NSCM/152/">M
 odeling of carotid artery hemodynamics towards a CFD database for stroke r
 isk assessment</a>\nby Anna Hundertmark (Rheinland-Pfälzische  Technische
  Universität) as part of Nečas Seminar on Continuum Mechanics\n\nLecture
  held in Room K3\,  Faculty of Mathematics and Physics\, Charles Universit
 y\, Sokolovská 83  Prague 8..\n\nAbstract\nIn medicine\, the risk assessm
 ent of strokes caused by pathological\nirregularities in the bifurcation o
 f the carotid artery plays a major\nrole in the patient's optimal treatmen
 t decision.\nThis decision-making process can be greatly enhanced by detai
 led flow\nfield data obtained from simulations using patient-specific arte
 rial\nmorphologies. We present our numerical modeling approach to create a
  CFD\ndatabase that can guide stroke risk assessment\, including hemodynam
 ic shear risk\nmetrics. We investigate the multi-directional behavior of w
 all shear\nstress (WSS) based on specially\nconstructed longitudinal tange
 nt vectors using a center-line projection\napproach and present the utilit
 y of longitudinal WSS evaluation for\ndetecting opposing or transverse WSS
  in slow  patient-specific flow. In\nour fluid-structure interaction model
 \,\nwe generalize the assumption of linear elasticity by a strain-dependen
 t\nelastic modulus that is consistent with laboratory measurements of\ncom
 pliance and distensibility. Finally\, we present the established\nworking 
 pipeline to generate CFD\ndata for a large number of patient-specific geom
 etries. Created\nhemodynamic datasets can be used for visual atlases and c
 omparative\nanalysis or explored by neural networks.\n
LOCATION:https://researchseminars.org/talk/NSCM/152/
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