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SUMMARY:Valentin Calisti (Institute of Mathematics\, Czech Academy of Scie
 nces)
DTSTART:20231030T144000Z
DTEND:20231030T161000Z
DTSTAMP:20260405T174415Z
UID:NSCM/116
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/NSCM/116/">M
 inimization of blood damage induced by non-Newtonian fluid flows in moving
  domains</a>\nby Valentin Calisti (Institute of Mathematics\, Czech Academ
 y of Sciences) as part of Nečas Seminar on Continuum Mechanics\n\nLecture
  held in Room K3\,  Faculty of Mathematics and Physics\, Charles Universit
 y\, Sokolovská 83  Prague 8..\n\nAbstract\nMany engineering works are int
 erested in the parametric optimization of\nblood pumps to minimize hemolys
 is (destruction of red blood cells).\nIn order to generalize this approach
 \, we study the shape continuity of a\ncoupled system of PDEs modeling blo
 od flows and hemolysis evolution in\nmoving domains\, governed respectivel
 y by generalized Navier-Stokes and\ntransport equations.\n\nFirst\, the sh
 ape continuity of the blood flow solutions is shown. This\ndevelopment\, w
 hich extends the one led in (Sokolowski\, Stebel\, Evol.\nEqu. Control The
 ory\, 2014) to the case of shear thinning fluids\, is\nbased on the recent
  progress made in (Nägele\, Ružička\, J. Differential\nEquations\, 2018
 )\, adapted to the present framework of a sequence of\nconverging moving d
 omains.\n\nAfter calculating blood flows solutions\, the velocity and stre
 ss fields\nare used as coefficients and r.h.s for the transport equation g
 overning\nthe evolution of the hemolysis rate. From this\, the shape conti
 nuity of\nthe hemolysis rate is also proved.\n\nFinally\, these results al
 low to show the existence of minimum for a\nclass of shape optimization pr
 oblems based on the minimization of the\nhemolysis rate\, in the framework
  of moving domains.\n
LOCATION:https://researchseminars.org/talk/NSCM/116/
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