BEGIN:VCALENDAR VERSION:2.0 PRODID:researchseminars.org CALSCALE:GREGORIAN X-WR-CALNAME:researchseminars.org BEGIN:VEVENT SUMMARY:Calina Copos (Northeastern University) DTSTART:20261124T170000Z DTEND:20261124T180000Z DTSTAMP:20261115T010400Z UID:Modeling_and_Computation/100 DESCRIPTION:Title: Symmetry Breaking\, Directed Movement\, and Organized T issue Response from Local Interactions\nby Calina Copos (Northeastern University) as part of Northwestern Applied Mathematics Seminar\n\nLecture held in M416 Tech Northwestern Evanston IL.\n\nAbstract\nPattern formatio n and symmetry breaking have long been areas of interest in applied mathem atics. In living systems\, these questions take on additional complexities : molecular interactions generate dynamic intracellular structures\, indiv idual cells develop persistent migratory behaviors\, and populations of ce lls coordinate their dynamics to produce spatiotemporal patterns. A centra l question is how do biological systems break symmetry\, select among comp eting dynamical states\, and coordinate response across scales? \n\nUsing cell doublets as the smallest nontrivial collective unit\, I will discuss mathematical models\, computational methods\, and dynamical systems approa ches for investigating how local feedback\, geometry\, and confinement sha pe these collective dynamical states. We examine how mechanochemical inter actions generate directional and coordinated migration\, biases\, and how nonlinear feedback and spatial coupling give rise to coherent oscillations \, traveling waves\, and other patterns. Extending these principles to lar ger cell clusters and tissues reveals emergent organization with implicati ons for development\, wound healing\, and limb regeneration. These example s illustrate how mathematical models can bridge scales and uncover princip les by which local interactions generate global organization.\n LOCATION:https://researchseminars.org/talk/Modeling_and_Computation/100/ END:VEVENT END:VCALENDAR