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SUMMARY:Badal Joshi (California State University San Marcos)
DTSTART:20210916T153000Z
DTEND:20210916T160000Z
DTSTAMP:20260421T124005Z
UID:MoRN/29
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/MoRN/29/">Dy
 namic Absolute Concentration Robustness</a>\nby Badal Joshi (California St
 ate University San Marcos) as part of Seminar on the Mathematics of Reacti
 on Networks\n\n\nAbstract\nOutput or functional robustness in biochemical 
 systems has been experimentally observed in the IDHKP-IDH glyoxylate bypas
 s regulation system and the EnvZ/OmpR system in E. coli. To model output r
 obustness\, we define the notion of dynamic absolute concentration robustn
 ess (dynamic ACR) in systems of ODEs. A species in a biochemical reaction 
 network has dynamic ACR if its concentration converges to the same positiv
 e value irrespective of overall initial conditions. Dynamic ACR builds on 
 the notion of static ACR wherein the concentration of a species has the sa
 me value in any positive steady state. We will define  stronger and weaker
  forms of both static and dynamic ACR along with various naturally occurri
 ng domains/basins for each. We will give a complete classification of smal
 l networks\, using both algebraic and topological characterization\, by th
 eir static ACR\, strong static ACR\, dynamic ACR\, and weak dynamic ACR pr
 operties.\n
LOCATION:https://researchseminars.org/talk/MoRN/29/
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