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SUMMARY:Nicola Vassena (FU Berlin)
DTSTART:20210513T153000Z
DTEND:20210513T160000Z
DTSTAMP:20260421T124252Z
UID:MoRN/26
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/MoRN/26/">Si
 gn-sensitivity of metabolic networks: which structures determine the sign 
 of the responses</a>\nby Nicola Vassena (FU Berlin) as part of Seminar on 
 the Mathematics of Reaction Networks\n\n\nAbstract\nPerturbations are ubiq
 uitous in metabolism. A central tool to understand\ntheir effect is sensit
 ivity analysis\, which investigates how the network\nresponds to external 
 perturbations. In this talk we follow a structural\napproach\, only based 
 on the network stoichiometry and not requiring any\nquantitative knowledge
  of the reaction rates. We consider perturbations of\nreaction rates\, at 
 equilibrium\, and we investigate the responses of the\nreaction fluxes. We
  focus in particular on the sign of such responses\,\ni.e. whether a respo
 nse is positive\, negative or whether its sign depends\non the reaction ra
 tes parameters. We identify and describe certain kernel\nvectors of the st
 oichiometric matrix\, which are the main players in the\nsign description.
 \n
LOCATION:https://researchseminars.org/talk/MoRN/26/
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