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SUMMARY:Marie E. Rognes
DTSTART:20261014T070000Z
DTEND:20261014T080000Z
DTSTAMP:20261024T105616Z
UID:MathMAC/65
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/MathMAC/65/"
 >Exciting times: high-fidelity modeling of living tissues</a>\nby Marie E.
  Rognes as part of Modelling of materials - theory\, model reduction and e
 fficient numerical methods (UNCE MathMAC)\n\n\nAbstract\nOver the last thr
 ee decades\, advances in bioimaging have revolutionized our ability to stu
 dy the structure and function of living systems. At the nano- to microscal
 e\, the new capabilities of cellular microscopy have resulted in the gener
 ation and wide availability of large-scale high-resolution imaging data\, 
 as strikingly exemplified by increasingly complex dense reconstructions of
  cortical tissue. In parallel\, research in scientific computing and compu
 tational mathematics have lead to the development of highly accurate\, eff
 icient and scalable numerical algorithms and their realization in open sci
 entific software. In this talk\, I will show how we over the last few year
 s have developed high-fidelity computational models of cellular and subcel
 lular physiology\, incorporating detailed geometric structure\, biophysica
 l dynamics and advanced cell imaging data. I will highlight key numerical 
 challenges - some that we have tackled and some open problems - and point 
 at future directions.\n
LOCATION:https://researchseminars.org/talk/MathMAC/65/
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