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SUMMARY:Prof. Dr. Dietrich M. Egli (Columbia University)
DTSTART:20221110T080000Z
DTEND:20221110T090000Z
DTSTAMP:20260423T022809Z
UID:MCB_LUMS/30
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/MCB_LUMS/30/
 ">Genome stability in embryonic development and reprogramming</a>\nby Prof
 . Dr. Dietrich M. Egli (Columbia University) as part of Colloquium zooming
  Molecular & Cellular Biology LUMS\n\n\nAbstract\nThe events occurring in 
 the beginning of human development are highly consequential for everything
  that follows\, but remain poorly understood and little investigated. Most
  human embryos fail to develop shortly after fertilization. This inefficie
 ncy in development is primarily caused by an unstable genome\, resulting i
 n aneuploidies\, DNA damage\, cell cycle arrest\, and in developing embryo
 s likely novel mutations. I will present our novel insight on how the embr
 yo replicates its DNA and how inefficiencies in DNA repair in the embryo s
 hape fertility as well as our health throughout life.\n
LOCATION:https://researchseminars.org/talk/MCB_LUMS/30/
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