BEGIN:VCALENDAR VERSION:2.0 PRODID:researchseminars.org CALSCALE:GREGORIAN X-WR-CALNAME:researchseminars.org BEGIN:VEVENT SUMMARY:Rolf Ryham (Fordham University) DTSTART:20200527T150000Z DTEND:20200527T160000Z DTSTAMP:20260423T041337Z UID:GSMMA/5 DESCRIPTION:Title: Me mbrane mechanics and rupture using coarse-grained hydrophobic attraction p otentials\nby Rolf Ryham (Fordham University) as part of Global Semina r on Mathematical Modeling and Applications\n\n\nAbstract\nThe talk goes o ver key modeling approaches for describing lipid bilayer membranes\, inclu ding particle-based simulation\, theoretical continuum mechanical descript ion\, fluid mechanical models and direct connections between theory and ex periment. The second part of the talk gives a mesoscopic formulation alter native to the standard Helfrich hamiltonian. Motivated by considerations o f hydrophobic surfaces that arise in theoretical studies of membrane fusio n\, the formulation is flexible enough to resolve the details of molecular transitions while retaining the continuum features of bilayer away from t he transitions. The framework assumes coarse-grained lipid 'particles'\, t hat interact through the solution of an appropriate second order elliptic PDE in the aqueous phase. Boundary conditions on each particle directly mo del the amphiphilic property of lipid\, and lead to\, as simulation output s\, elastic properties previously assumed in membrane mechanics. A manuscr ipt in SIAM J Multiscale Modeling and Simulation (2020) summarizes some of the results.\n\nmeeting has ended\n LOCATION:https://researchseminars.org/talk/GSMMA/5/ END:VEVENT END:VCALENDAR