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SUMMARY:Isabel Darcy (University of Iowa - USA)
DTSTART:20230922T160000Z
DTEND:20230922T170000Z
DTSTAMP:20260423T023055Z
UID:GEOTOP-A/51
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/GEOTOP-A/51/
 ">Modeling knotted proteins with tangles</a>\nby Isabel Darcy (University 
 of Iowa - USA) as part of GEOTOP-A seminar\n\n\nAbstract\nWe prove using t
 he mathematics of tangles that if a protein terminus passing through a sin
 gle loop results in a locally knotted protein\, then Taylor's twisted hair
 pin model is the most likely method for creating such knots. In this case 
 the knotted products will all be twist knots. If we assume a right-handed 
 chirality bias\, which is common in proteins\, then  the majority of these
  twist knots will be  right-handed trefoils ($+3_1$)\, followed by left-ha
 nded trefoils ($-3_1$)\, achiral figure eight knots ($4_1$) and right-hand
 ed five crossing twist knots ($-5_2$). An alternative pathway has been obs
 erved computationally where a terminus passes through two loops.  We use 3
 -string tangle analysis to model this pathway.  This is joint work with Ga
 rrett Jones and Puttipong Pongtanapaisan.\n
LOCATION:https://researchseminars.org/talk/GEOTOP-A/51/
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