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BEGIN:VEVENT
SUMMARY:Amaury Lambert (Sorbonne)
DTSTART:20201009T150000Z
DTEND:20201009T160000Z
DTSTAMP:20260422T212553Z
UID:ProbandBio/1
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/ProbandBio/1
 /">Genealogy of one or many genes</a>\nby Amaury Lambert (Sorbonne) as par
 t of Probability and Biology mini-series\n\n\nAbstract\nThis lecture is pa
 rt of the IICD & Probability and Society Initiative Joint Seminar Series\,
  mini-series on Evolutionary processes and patterns of biodiversity.\n\nIn
  this lecture\, we explain how the genetic diversity of a sample of indivi
 duals can be characterized and scales with the size of the population wher
 e it is taken from\, via the study of gene genealogies and Kingman’s coa
 lescent. Next\, we display tools describing how genealogies of different g
 enes are coupled by the effect of recombination. We apply these tools to a
  practical problem (how to infer past demography given a handful of genome
 s) and to a theoretical question (if ancestral genomes were all painted in
  distinct colors\, how would the mosaic of colors on the genome look like 
 in the long run?).\n
LOCATION:https://researchseminars.org/talk/ProbandBio/1/
END:VEVENT
BEGIN:VEVENT
SUMMARY:Amaury Lambert (Sorbonne)
DTSTART:20201016T150000Z
DTEND:20201016T160000Z
DTSTAMP:20260422T212553Z
UID:ProbandBio/2
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/ProbandBio/2
 /">Formation of new species</a>\nby Amaury Lambert (Sorbonne) as part of P
 robability and Biology mini-series\n\n\nAbstract\nThis lecture is part of 
 the IICD & Probability and Society Initiative Joint Seminar Series\, mini-
 series on Evolutionary processes and patterns of biodiversity.\n\nThe evol
 utionary history of species can be represented by a tree called phylogeny.
  We explain how birth-death processes are standardly used to model the div
 ersification of species (speciation\, extinction) and how their parameters
  can be inferred from the phylogeny\, notably via the so-called coalescent
  point process. We then expose the species paradox and explain how to mode
 l the formation of new species from first principles. We apply these model
 s to an empirical question (why are species phylogenies imbalanced?) and t
 o a theoretical question (how does the graph describing the ability to int
 erbreed look like?).\n
LOCATION:https://researchseminars.org/talk/ProbandBio/2/
END:VEVENT
BEGIN:VEVENT
SUMMARY:Amaury Lambert (Sorbonne)
DTSTART:20201023T150000Z
DTEND:20201023T160000Z
DTSTAMP:20260422T212553Z
UID:ProbandBio/3
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/ProbandBio/3
 /">Coevolving genes and species</a>\nby Amaury Lambert (Sorbonne) as part 
 of Probability and Biology mini-series\n\n\nAbstract\nThis lecture is part
  of the IICD & Probability and Society Initiative Joint Seminar Series\, m
 ini-series on Evolutionary processes and patterns of biodiversity.\n\nDue 
 to recombination and to hybridization between species\, the genealogies of
  genes\, even sampled from distantly related species\, are usually differe
 nt at different genes\, and (so) distinct from the species tree. We review
  models coupling gene trees and species tree\, including the popular multi
 species coalescent. We apply these models to a practical problem (how to c
 luster a sample of genomes into putative species) and to a theoretical que
 stion (characterization of nested coalescents describing jointly gene tree
 s and species tree and study of their behavior close to the present).\n
LOCATION:https://researchseminars.org/talk/ProbandBio/3/
END:VEVENT
BEGIN:VEVENT
SUMMARY:Alison Etheridge (Oxford)
DTSTART:20201106T160000Z
DTEND:20201106T170000Z
DTSTAMP:20260422T212553Z
UID:ProbandBio/7
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/ProbandBio/7
 /">Spatial population models</a>\nby Alison Etheridge (Oxford) as part of 
 Probability and Biology mini-series\n\n\nAbstract\nThis lecture is part of
  the IICD & Probability and Society Initiative Joint Seminar Series\, mini
 -series on Some mathematical models of evolution.\n\nHow does spatial stru
 cture of a population interact with genetic drift? And what about the inte
 raction with selection? We introduce some (classical and not so classical)
  mathematical models that aim to capture these key forces acting on a popu
 lation and\, as time permits\, investigate the way in which spatial struct
 ure influences the effectiveness of natural selection.\n
LOCATION:https://researchseminars.org/talk/ProbandBio/7/
END:VEVENT
BEGIN:VEVENT
SUMMARY:Alison Etheridge (Oxford)
DTSTART:20201113T160000Z
DTEND:20201113T170000Z
DTSTAMP:20260422T212553Z
UID:ProbandBio/8
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/ProbandBio/8
 /">Expanding populations</a>\nby Alison Etheridge (Oxford) as part of Prob
 ability and Biology mini-series\n\n\nAbstract\nThis lecture is part of the
  IICD & Probability and Society Initiative Joint Seminar Series\, mini-ser
 ies on Some mathematical models of evolution.\n\nThe way in which a popula
 tion expands its range\, or the way in which a favored genetic type spread
 s through a population\, is often modeled by the classical Fisher-KPP equa
 tion or its stochastic counterpart\, both of which exhibit traveling wave 
 solutions. At the front of the expanding wave\, where there is little comp
 etition for space\, individuals can reproduce quickly and produce large fa
 milies. The advantage that the uncrowded nature of their environment gives
  them is such that they can even afford to carry some disadvantageous muta
 tions\, with the result that individuals in the front are inherently less 
 fit than those in the bulk\, an effect called expansion load. We investiga
 te expansion load (mostly numerically)\, particularly in the presence of g
 enetic drift.\n
LOCATION:https://researchseminars.org/talk/ProbandBio/8/
END:VEVENT
BEGIN:VEVENT
SUMMARY:Alison Etheridge (Oxford)
DTSTART:20201120T160000Z
DTEND:20201120T170000Z
DTSTAMP:20260422T212553Z
UID:ProbandBio/9
DESCRIPTION:Title: <a href="https://researchseminars.org/talk/ProbandBio/9
 /">The infinitesimal model and evolutionary rescue</a>\nby Alison Etheridg
 e (Oxford) as part of Probability and Biology mini-series\n\n\nAbstract\nT
 his lecture is part of the IICD & Probability and Society Initiative Joint
  Seminar Series\, mini-series on Some mathematical models of evolution.\n\
 nMany of the classical models of natural selection acting on a population 
 suppose that an individual's fitness is determined by its type at some sma
 ll number of genetic loci. However\, in many scenarios selection is acting
  on a trait that is determined by the accumulation of small effects at a v
 ery large number of loci. To model this situation\, we introduce the `infi
 nitesimal model' under which within-family trait values are normally distr
 ibuted (although the values across the whole population could be far from 
 normal)\, and then use it to investigate `evolutionary rescue' - the proce
 ss through which maladapted individuals are able to evolve a positive grow
 th rate fast enough to avoid extinction.\n
LOCATION:https://researchseminars.org/talk/ProbandBio/9/
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